The 25 Most Dangerous Prescription Drugs

Most Dangerous Prescription Drugs | Just Believe Recovery PA

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The 25 Most Dangerous Prescription Drugs

Using data culled from the Food and Drug Administration from 2004-2015, HealthGrove, a health data website, examined 150 medications that have the highest number of adverse reactions and ranked them using the percentage of these reactions that were considered serious.

The top 50 medications with the most severe adverse reactions are thought to be the most dangerous. While some over-the-counter medicines made the top 50 list, the top 25 only consists of the most dangerous prescription drugs.

Some of these medications are not deemed dangerous if taken appropriately but can be harmful if too much is used or they are combined with other substances, such as alcohol.

According to the National Council on Patient Information, approximately one-third of all American stated that they “combine medications when treating multiple symptoms.”

Here is the top 25 most dangerous prescription drugs. You can view the entire list here.

#25. Diazepam (Diastat, Diastat Pediatric) – Anticonvulsant

Percent of Serious Reactions: 81%
Number of Serious Reactions: 31,794
Number of Reported Reactions: 38,978

#24. Rivaroxaban (Xarelto) – Anticoagulant

Percent of Serious Reactions: 81%
Number of Serious Reactions: 33,317
Number of Reported Reactions: 41,114

The most common serious reactions were gastrointestinal bleeding, pulmonary embolism, and deep vein thrombosis.

#23. Alendronate (Fosamax) – Calcium Regulator

Percent of Serious Reactions: 82%
Number of Serious Reactions: 39,257
Number of Reported Reactions: 47,769

The most common serious reactions included femur fractures and falls.

#22. Clopidogrel (Plavix) – Platelet Aggregation Inhibitor

Percent of Serious Reaction: 82%
Number of Serious Reactions: 70,205
Number of Reported Reactions: 85,447

The most common serious reactions include heart attack, gastrointestinal bleeding, and stroke.

#21. Furosemide (Lasix) – Cardiovascular Agent

Percent of Serious Reactions: 82%
Number of Serious Reactions: 102,865
Number of Reported Reactions: 124,020

The most common serious reactions were difficulty breathing, congestive heart failure, and acute renal failure.

#20. Digoxin (Digitek, Diox, Lanoxin) – Cardiovascular Agent

Percent of Serious Reactions: 83%
Number of Serious Reactions: 30,355
Number of Reported Reactions: 36,506

The most common serious reactions were difficulty breathing, atrial fibrillation, and congestive heart failure.

#19. Spironolactone (Aldactone) – Cardiovascular Agent

Percent of Serious Reactions: 84%
Number of Serious Reactions: 28,871
Number of Reported Reactions: 34,336

The most common serious reactions were difficulty breathing and acute renal failure.

#18. Allopurinol (Aloprim) – Antigout

Percent of Serious Reactions: 84%
Number of Serious Reactions: 30,921
Number of Reported Reactions: 36,755

#17. Morphine (Ms Contin, Avinza,, Morphabond) – Analgesic

Percent of Serious Reactions: 84%
Number of Serious Reactions: 37,986
Number of Reported Reactions: 44,906

The most common serious reaction was death.

#16. Ondansetron (Zofran, Zuplenz) – Antiemetic

Percent of Serious Reactions: 85%
Number of Serious Reactions: 31,005
Number of Reported Reactions: 36,133

#15. Ramipril (Altace) – Antihypertensive

Percent of Serious Reactions: 85%
Number of Serious Reactions: 32,374
Number of Reported Reactions: 37,895

The most common serious reactions were difficulty breathing, acute renal failure, and drug interaction

#14. Rosiglitazone (Avania) – Antidiabetic

Percent of Serious Reactions: 85%
Number of Serious Reactions: 87,352
Number of Reported Reactions: 101,873

The most common serious reactions were heart attack, congestive heart failure, and stroke.

#13. Medroxyprogesterone (Provera, Alti-Mpa) – Endocrine-Metabolic Agent

Percent of Serious Reactions: 89%
Number of Serious Reactions: 34,018
Number of Reported Reactions: 38,079

The most common serious reactions were breast cancer and metastatic breast cancer.

#12. Lenalidomide (Revlimid) – Immune Modulator

Percent of Serious Reactions: 89%
Number of Serious Reactions: 69,123

The most common serious reactions were death and pneumonia.

#11. Methylprednisolone (Medrol, Methylpred-Dp) – Endocrine-Metabolic Agent

Percent of Serious Reactions: 90%
Number of Serious Reactions: 30,040
Number of Reported Reactions: 33,095

The most common serious reactions were fever and pneumonia.

#10. Metoclopramide (Metozolv, Reglan) – Antiemetic

Percent of Serious Reactions: 91%
Number of Serious Reactions: 32,757
Number of Reported Reactions: 35,623

The most common serious reactions were tardive dyskinesia and extrapyramidal disorder, both related to uncontrollable, stiff, jerky movements of the face and body.

#9. Infliximab (Remicade) – Immunological Agent

Percent of Serious Reactions: 91%
Number of Serious Reactions: 68,167
Number of Reported Reactions: 74,738

The most common serious reactions were difficulty breathing and infusion-related reactions.

#8. Tacrolimus (Protopic) – Antipsoriatic

Percent of Serious Reactions: 92%
Number of Serious Reactions: 27,964
Total Number of Reported Reactions: 30,262

#7. Zoledronic Acid (Reclast, Zometa) – Calcium Regulator

Percent of Serious Reactions: 93%
Number of Serious Reactions: 35,581
Number of Reported Reactions: 38,016

#6. Dexamethasone ( Baycadron Elixer, Decadron, Dekpak 13 Day Taperpak, Dexamethasone Intensol, Dexpak) – Endocrine-Metabolic Agent

Percent of Serious Reactions: 93%
Number of Serious Reactions: 38,966
Number of Reported Reactions: 41,636

#5. Clozapine (Clozaril, Versacloz) – Antipsychotic

Percent of Serious Reactions: 95%
Number of Serious Reactions: 29,470
Number of Reported Reactions: 30,914

The most common serious reactions were death and an increase in white blood cells.

#4. Rituximab (Rituxan) – Antineoplastic Agent

Percent of Serious Reactions: 96%
Number of Serious Reactions: 30,014
Number of Reported Reactions: 31,157

The most common serious reactions were death and fever with signs of infection.

#3. Bevacizumab (Avastin) – Immunological Agent

Percent of Serious Reactions: 96%
Number of Serious Reactions: 39,957
Number of Reported Reactions: 41,281

The most common serious reactions were death, disease progression, and diarrhea.

#2. Prednisolone (Bubbli-Pred, Cotolone, Flo-Pred, Millipred, Orapred, Pediapred, Prelone, Veripred 20, Pms-Prednisolone (Endocrine-Metabolic Agent)

Percent of Serious Reactions: 96%
Number of Serious Reactions: 42,323
Number of Reported Reactions: 43,817
The most common serious reactions were fever, pneumonia, and difficulty breathing.

#1. Cyclophosphamide (Cytoxan) – Antineoplastic Agent

Percent of Serious Reactions: 97%
Number of Serious Reactions: 33,128
Number of Reported Reactions: 34,076

The most common serious reactions were fever with infection.

~ G. Nathalee Serrels, M.A., Psychology

References For 25 Most Dangerous Prescription Drugs

http://www.fox25boston.com/news/the-50-most-dangerous-drugs-1/570088542

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