Drug Found To Reverse Brain Damage From Alcohol

Brain Damage From Alcohol | Just Believe Recovery PA

In This Article

Drug Found To Reverse Brain Damage From Alcohol Abuse

Scientists at the Queensland University of Technology have discovered that a drug used to treat anxiety could help reverse brain damage from alcohol abuse by regenerating brain cells.

Research on mice revealed that two weeks of every day treatment with the drug tandospirone negated the effects of nearly four months of alcohol binging on neurogenesis, which is the brain’s ability to grow and regenerate neurons.

Tandospirone is an anti-anxiety and antidepressant medication used in China and Japan. It is a member of the azapirone drug classification and is closely related to other drugs such as buspirone and gepirone.

Tandospirone acts on a serotonin receptor, but this is the first time it has been found to reverse the brain regeneration deficits caused by heavy alcohol use. Researchers also revealed in the study that the drug could stop anxious behaviors linked to alcohol withdrawal symptoms as well as a notable reduction in alcohol intake.

From the study:

“Using paradigm to model chronic long-term binge-like voluntary alcohol consumption in mice, we show that the selective partial activation of 5-HT1A receptors by tandospirone…prevents alcohol withdrawal-induced anxiety in a battery of behavioral tests…which is accompanied by a robust decrease in binge-like ethanol intake…”

Study author neuroscientist Professor Selena Bartlett from QUT’s Institute of Health and Biomedical Innovation stated the following in a news release:

“We know that with heavy drinking you are inhibiting your ability to grow new neurons, brain cells. Alcohol is specifically very damaging for neurons.”

“This is a novel discovery that tandospirone can reverse the deficit in neurogenesis caused by alcohol.”

~ G. Nathalee Serrels, M.A., Psychology

References

https://www.qut.edu.au/news?id=127396

Arnauld Belmer, Omkar L. Patkar, Vanessa Lanoue, Selena E. Bartlett. 5-HT1A receptor-dependent modulation of emotional and neurogenic deficits elicited by prolonged consumption of alcohol. Scientific Reports, 2018; 8 (1) DOI: 10.1038/s41598-018-20504-z

Just Believe Recovery is a fully licensed, Joint Commission accredited, comprehensive drug and alcohol treatment center located in Carbondale, Pennsylvania

Let's Connect

🔒 Your information is safe & secure

Sidebar Contact

  • This field is for validation purposes and should be left unchanged.
How to Get Meth Out of Your System | Just Believe Recovery PA
Detox

How to Get Meth Out of Your System

Medical detox is widely considered the safest, most comfortable, and effective method of treating methamphetamine (meth) withdrawal. If a person is using meth, detox can

Read More »
Are You an Adult Child? | Just Believe Recovery PA
Mental Health

Are You an Adult Child?

An adult child is a term used to describe an adult that experienced living with an addict or alcoholic parent or parents as a child.

Read More »